Human amniotic membrane graft removal and histopathologic evaluation following closure of a full thickness macular hole.

ABSTRACT:

Purpose

Human amniotic membrane (hAM) grafts have been used to close persistent macular holes in recent years. The results from these surgeries are promising with improved closure rate and vision. However, there is lack of data for what happens to these membranes and how long the tissue should remain inside the patient's eyes. We report a case of hAM graft removal 6 months after closure of a persistent macular hole and the histopathology result of the removed hAM graft.

Observations

This is a report of a 57-year-old male patient that presented with hand motion vision, bullous, macula off rhegmatogenous retinal detachment in his right eye with multiple retinal holes and tears. Patient had 25G pars plana vitrectomy (PPV) with membrane peel and perfluoro-n-octane (PFO), silicon

SUBMITTER: Patel H 

PROVIDER: S-EPMC11770488 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature