Alterations of lung and gut microbiota in sodium butyrate alleviating heat stress-induced lung injury of broilers.

ABSTRACT: Heat-induced stress has a significant impact on the health of broilers. It induces panting behavior and elevates oxygen consumption, leading to considerable strain on the broiler lungs. However, the precise effects of heat stress on lung injury, along with changes in the lung and gut microbiota, are not yet fully understood. In our study, Arbor Acres (AA) broilers were employed as a model to assess the efficacy of sodium butyrate (SB) in mitigating heat stress-induced lung injury, while concurrently exploring the potential role of lung and gut microbiota in this phenomenon. Heat stress negatively affected broilers, particularly leading to lung injury, which was alleviated by dietary supplementation with SB. However, antibiotic-induced dysbiosis of the microbiota diminished the protective e

SUBMITTER: Niu Q 

PROVIDER: S-EPMC11770502 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature