Plasmonic Nanoparticles for Photothermal Therapy: Benchmarking of Photothermal Properties and Modeling of Heating at Depth in Human Tissues.

ABSTRACT: Many different types of nanoparticles have been developed for photothermal therapy (PTT), but directly comparing their efficacy as heaters and determining how they will perform when localized at depth in tissue remains complex. To choose the optimal nanoparticle for a desired hyperthermic therapy, it is vital to understand how efficiently different nanoparticles extinguish laser light and convert that energy to heat. In this paper, we apply photothermal mass conversion efficiency (η _m ) as a metric to compare nanoparticles of different shapes, sizes, and conversion efficiencies. We selected silica-gold nanoshells (AuNShells), gold nanorods (AuNRs), and gold nanostars (AuNStars) as three archetypal nanoparticles for PTT and measured the η _m of each to dem

SUBMITTER: Skinner WH 

PROVIDER: S-EPMC11770747 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature