Essential oils from Amorpha fruticosa against hepatocellular carcinoma based on network pharmacology.

ABSTRACT:

Background

Amorpha fruticosa was used for treating burn, ambustion, carbuncle, and eczema in the traditional Chinese medicine. Although more and more attention has been paid to its biological activity recently, the antitumor activities of the essential oils (EOs) extracted from its leaves (AFLEO) and flowers (AFFEO), and their molecular mechanisms have never been reported up to now. The objective of present study was to examine the chemical compositions of AFLEO and AFFEO, then investigate the effects and pharmacological mechanism of EOs against hepatocellular carcinoma (HCC).

Methods

The chemical compositions of EOs were examined using gas chromatography-mass spectrometry (GC-MS). The inhibitory effect of the EOs on HCC was evaluated by MTT assay. The detected components of

SUBMITTER: Liu Y 

PROVIDER: S-EPMC11771004 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature