Outcomes following intradetrusor onabotulinumtoxinA in a national cohort of nursing home residents.

ABSTRACT:

Objectives

To determine predictors of treatment success and complications following intradetrusor onabotulinumtoxinA injections among a large cohort of nursing home (NH) residents, representing one of the most frail and vulnerable populations in the United States.

Materials and methods

This is a retrospective cohort study of long-stay NH residents who underwent onabotulinumtoxinA injections between 2014 and 2016. Residents were identified using the Minimum Data Set (MDS) linked to Medicare claims. Frailty was measured using the Claims-based Frailty Index and socioeconomic status using the Area Deprivation Index (ADI; higher ADI = increasing social deprivation). The primary outcome was treatment success, defined as repeat onabotulinumtoxinA injection within 1 year of index in

SUBMITTER: Dreyfuss LD 

PROVIDER: S-EPMC11771503 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature