Association Between Rheumatoid Arthritis Disease Activity and Periodontitis Defined by Tooth Loss: Longitudinal and Cross-Sectional Data From Two Observational Studies.

ABSTRACT:

Objective

To analyze the effect of tooth loss/periodontitis on disease activity in early and established rheumatoid arthritis (RA).

Methods

Participants of the Course And Prognosis of Early Arthritis (CAPEA) early arthritis cohort reported their number of teeth at baseline. The number of teeth had been validated as a predictor of periodontitis. Clinical end points, including disease activity score (Disease Activity Score in 28 joints using the erythrocyte sedimentation rate [ESR]), swollen joint count (SJC), ESR, and C-reactive protein level were collected at baseline, 3, 6, 12, 18, and 24 months. We used linear mixed regression models to estimate the association between tooth loss and clinical end points over time in early arthritis. For established RA, we analyzed cross-se

SUBMITTER: Albrecht K 

PROVIDER: S-EPMC11771685 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature