Genomic characteristics and molecular epidemiology of MRSA from medical centers in Mexico: Results from the Invifar network.

ABSTRACT:

Introduction

The methicillin-resistant Staphylococcus aureus (MRSA) genome varies by geographical location. This study aims to determine the genomic characteristics of MRSA using whole-genome sequencing (WGS) data from medical centers in Mexico and to explore the associations between antimicrobial resistance genes and virulence factors.

Methods

This study included 27 clinical isolates collected from sterile sites at eight centers in Mexico in 2022 and 2023. Antibiotic susceptibility testing was performed using VITEK 2. In addition, WGS was performed using a NovaSeq platform, and a bioinformatic analysis was conducted using several tools.

Results

In this study, 21 strains were CC5, five were CC8, and one was CC93. Moreover, six strains were identified as ST5(CC5)-MRSA-

SUBMITTER: Echaniz-Aviles G 

PROVIDER: S-EPMC11771916 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature