Scrub typhus in pregnancy: A 10-year multicenter study in resource-limited settings in China.

ABSTRACT:

Background

Despite its association with high mortality rates and negative fetal outcomes, large-scale epidemiological studies on scrub typhus (ST) during pregnancy remain scarce.

Methods

We conducted a retrospective, multicenter study by collecting 260 pregnant women with ST in China across a 10-year time period to evaluate how clinical characteristics changed over this time and identify risk factors for poor fetal outcome.

Results

In total, 78.5% (n = 204) presented with pathognomonic eschars or ulcers, and 75.4% (n = 196) had Weil-Felix test, in which 46.4% (n = 91) had a titer of ≥1:160 for OXK. A higher proportion of patients with pneumonia (18.7% vs. 9.5%, p = 0.033) and a longer length of hospitalization (7 vs. 6 days, p = 0.007) were seen in laboratory confirme

SUBMITTER: Zhao P 

PROVIDER: S-EPMC11771934 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature