Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats.

ABSTRACT: Millions of patients and their caretakers live and deal with the devastating consequences of spinal cord injury (SCI) worldwide. Despite outstanding advances in the field to both understand and tackle these pathologies, a cure for SCI patients, with their peculiar characteristics, is still a mirage. One of the most promising therapeutic strategies to date for these patients involves the use of epidural electrical stimulation. In this context, electrically active materials such as graphene and its derivates become particularly interesting. Indeed, solid evidence of their capacity to closely interact with neural cells and networks is growing. Encouraged by previous findings in our laboratory on the exploration of 3D porous reduced graphene oxide (rGO) scaffolds in chronic cervical hemisected

SUBMITTER: Zaforas M 

PROVIDER: S-EPMC11772149 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature