Platelet count and retinopathy of prematurity, a systematic review and meta-analysis.

ABSTRACT:

Objective

This study aims to investigate the relationship between platelet count (PLT) and retinopathy of prematurity (ROP), with the goal of identifying a straightforward screening method for the early detection of ROP.

Methods

A systematic search was conducted in PubMed, EMBASE, Web of Science, Cochrane Library, and ClinicalTrials.gov from January 2005 to 26 September 2023. Subsequently, a subgroup analysis was performed.

Results

This meta-analysis included ten studies involving 1762 neonates, with 747 cases of ROP identified. The pooled analysis indicated a significant decrease in mean platelet count among the ROP group compared to the non-ROP group (mean difference: -18.65, 95% confidence interval: -22.80 to -14.50, P < .00001). Subgroup analysis indicated

SUBMITTER: Zeng Q 

PROVIDER: S-EPMC11772428 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature