Micronutrient deficiencies and new-onset atrial fibrillation in a community-based cohort: data from PREVEND.

ABSTRACT:

Aim

Malnutrition has been linked to cardiovascular diseases. Both selenium and iron deficiency have been associated with worse prognosis in patients with heart failure (HF). Yet, little is known about the role of micronutrients in the development of atrial fibrillation (AFib). In this study, we aimed to elucidate the association of micronutrient deficiencies with new-onset AFib.

Methods

Selenium, magnesium, and iron parameters were measured in a well-characterized prospective cohort study (N = 5452). Selenium deficiency was defined as serum selenium < 70 μg/L, iron deficiency as serum ferritin < 30 μg/L, and magnesium deficiency as plasma magnesium < 0.85 mmol/L. New-onset AFib was the primary outcome. Additionally, we tested for previously reported effect-modifiers where ap

SUBMITTER: Al-Mubarak AA 

PROVIDER: S-EPMC11772465 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature