Impact of comorbid constipation on the survival of patients with heart failure: a multicenter, prospective cohort study conducted in Japan.

ABSTRACT:

Background

Constipation frequently affects heart failure patients because of medication side effects and physiological effects of the condition. Although recent speculation suggests that comorbid constipation may affect cardiovascular disease onset and survival rates, this relationship remains unclear. We examined the effect of comorbid constipation on the survival of patients with heart failure.

Methods

We conducted a multicenter prospective cohort study (the Kochi YOSACOI study) of patients hospitalized for acute decompensated heart failure. The influence of comorbid constipation on survival was evaluated using Cox regression analysis with 2-year survival as the index. Patients were divided into two groups based on the presence of comorbid constipation. The patient backgro

SUBMITTER: Ishida T 

PROVIDER: S-EPMC11772488 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature