Comprehensive prognosis assessment of cardiovascular magnetic resonance parametric mapping in light chain amyloidosis.

ABSTRACT:

Background

Recent evidence underscores the importance of cardiovascular magnetic resonance (CMR) in light chain amyloidosis (AL amyloidosis). We aimed to comprehensively assess the prognostic significance of CMR parametric mapping in AL amyloidosis.

Methods

This prospective study consecutively included AL amyloidosis patients who underwent CMR imaging before therapy. The statistical analyses included T2, extracellular volume, and native T1 as variates under investigation, adjusted for well-established prognostic markers. The outcome was death from any cause.

Results

In total, 195 patients (age, 57.2 ± 9.1 years; male/female, 123/72) were recruited. At the median follow-up time (19 months), the survival probability was approximately 67.2% (131/195). T >44 ms, extracell

SUBMITTER: Li X 

PROVIDER: S-EPMC11773017 | biostudies-literature | 2025 Summer

REPOSITORIES: biostudies-literature