Dissociable ventral and dorsal sensorimotor functional circuits linking the hypomanic personality traits to aggression via behavioral inhibition system.

ABSTRACT: Hypomanic personality traits (HPT) are susceptibility markers for psychiatric disorders, particularly bipolar disorder, and are strongly associated with aggressive behaviors. However, the neuropsychological mechanisms underlying this association remain unclear. This study utilized psychometric network analysis and Inter-Subject Representation Similarity Analysis (IS-RSA) to explore the neuropsychological circuits that link HPT to aggression in a large non-clinical population. Psychometric network analysis (n = 716) identified two key nodes: the Behavioral Inhibition System (BIS) and mood volatility, a core dimension of HPT. We observed a positive correlation between mood volatility and aggression, with BIS serving as a mediating factor. Task-based functional imaging (n = 53) further

SUBMITTER: Ge W 

PROVIDER: S-EPMC11773241 | biostudies-literature | 2025 Jan-Mar

REPOSITORIES: biostudies-literature