When to Use Rectangular Waveforms in Dielectrophoresis Application to Increase Separation and Sorting Efficiency.

ABSTRACT: In this study, the influence of using rectangular waveforms is comprehensively investigated on the separation and sorting efficiency of dielectrophoretic (DEP) processes. Besides positive effects on DEP experiments, cases of a diminished force due to rectangular waveforms are investigated and discussed. This investigation encompasses two primary experimental setups. First, microparticle-focusing experiments are carried out using a pair of electrodes within a microfluidic channel. Second, separation experiments are performed using a macroscopic insulator-based dielectrophoretic filter. The study reveals that harmonics of rectangular signals can have a positive impact on separation or sorting efficiency when compared to sinusoidal waveforms, provided that these harmonics contribute to the ov

SUBMITTER: Boldt NP 

PROVIDER: S-EPMC11773296 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature