Thioxanthone Synthesis from Thioureas through Double Aryne Insertion into a Carbon-Sulfur Double Bond.

ABSTRACT: Thioxanthone synthesis from o-silylaryl triflates and thioureas is disclosed. Double aryne insertion into the C═S double bond of thioureas and subsequent hydrolysis realized the facile preparation of thioxanthones. A simple reaction procedure and good accessibility of o-silylaryl triflates allowed us to synthesize a wide range of highly functionalized thioxanthones.

SUBMITTER: Kawada M 

PROVIDER: S-EPMC11773562 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature