Stereo- and Enantioselective Syntheses of (<i>Z</i>)-1,3-Butadienyl-2-carbinols via Bronsted Acid Catalysis.

ABSTRACT: A Brønsted acid-catalyzed enantioselective synthesis of (Z)-1,3-butadienyl-2-carbinols is developed. By employing a chiral phosphoric acid as the catalyst, a variety of 1,3-butadienyl-2-carbinols were obtained in good yields with excellent Z-selectivities and enantiopurities from α-alkyl-substituted homoallenyl boronates.

SUBMITTER: Chen M 

PROVIDER: S-EPMC11773566 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature