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Hyponatremia is associated with malignant brain edema after mechanical thrombectomy in acute ischemic stroke.


ABSTRACT:

Background

Hyponatremia (< 135 mmol/L) is the most common electrolyte disturbance in patients with stroke. However, few studies have reported the relationship between hyponatremia at admission and outcomes in patients with acute ischemic stroke (AIS) treated with mechanical thrombectomy (MT). This study is aimed to explore the association between hyponatremia and clinical outcomes following MT.

Methods

A retrospective study was conducted at our center. The primary outcome was postoperative malignant brain edema (MBE). The secondary outcomes included mortality and adverse function at the 90-day follow-up, which were defined as modified Rankin scale scores of 6 and > 2, respectively. Patients were classified into hyponatremia and nonhyponatremia groups based on their serum sod

SUBMITTER: Qian A 

PROVIDER: S-EPMC11773710 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature