Mortality and immunological indicators of men who have sex with men living with HIV on antiretroviral therapy: a 10-year retrospective cohort study in Southern China.

ABSTRACT:

Background

The proportion of people living with HIV (PLHIV) in Guangxi who are men who have sex with men (MSM) increased rapidly to nearly 10% in 2023; notably, over 95% of this particular population is currently receiving antiretroviral therapy (ART). This study aimed to describe the survival of MSM PLHIV, depict the characteristics and trends of changes in CD4⁺ T cell counts, CD4⁺/CD8⁺ T cell ratio, and viral load, and explore immunological indicators that may be related to mortality during different stages of treatment.

Methods

Immunological indicators of MSM PLHIV receiving ART were extracted and categorized into baseline, mid-treatment, and last values. These were then incorporated into the Cox models in the form of repeated measurements

SUBMITTER: Lu H 

PROVIDER: S-EPMC11773718 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature