Major heavy metals and human gut microbiota composition: a systematic review with nutritional approach.

ABSTRACT:

Background

The human gut microbiota has a critical role in several aspects of host homeostasis, such as immune development, metabolism, nutrition, and defense against pathogens during life. It can be sensitive to xenobiotics including drugs, diet, or even environmental pollutants, especially heavy metals (HMs). The findings of some previous studies are heterogeneous due to the inclusion of various types of study (human, and animal studies) and wide exposures (phthalate, bisphenol A, HMS, etc.), and no comprehensive systematic review has investigated the association between HMs exposure and human gut microbiota composition. Therefore, we carried out a systematic review of human observational studies to examine this association. PubMed, Scopus, ISI Web of Science, and Google Scholar

SUBMITTER: Rezazadegan M 

PROVIDER: S-EPMC11773724 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature