Changes in abdominal adipose tissues and ectopic fat depots during pregnancy are dissociated from gestational weight gain.

ABSTRACT:

Objective

The study objective was to evaluate changes in abdominal adipose tissue and ectopic fat during pregnancy and their associations with gestational weight gain (GWG) in women with overweight/obesity.

Methods

This study was a secondary analysis of a randomized controlled trial. Magnetic resonance scans were performed during gestational week (GW) 15, GW 32, and around birth to measure abdominal subcutaneous (SAT) and visceral (VAT) adipose tissues, liver fat, and muscle fat. Linear mixed models and multivariable linear regression analyses were utilized, adjusting for prepregnancy BMI, parity, and randomization.

Results

Among 119 women, VAT and SAT decreased from GW 15 to GW 32 but rebounded at birth; final levels were lower than at GW 15. Liver fat and muscle fat

SUBMITTER: Mogensen CS 

PROVIDER: S-EPMC11773999 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature