Abnormal functional hubs in migraine patients: a resting-state MRI analysis about voxel-wise degree centrality.

ABSTRACT: The purpose was to explore the spatial centrality of the whole brain functional network related to migraine and to investigate the potential functional hubs associated with migraine. 32 migraine patients and 55 healthy controls were recruited and they received resting-state functional magnetic resonance imaging voluntarily. Voxel-wise Degree Centrality (DC) was measured across the whole brain, and group differences in DC were compared. False Discovery Rate and permutation test (5000 times) were used for multiple comparisons. Finally, significant differences in functional connectivity (FC) between seeds and other brain regions were further researched by the seed-based approach. The correlation analyses between the changes in the brain function and clinical features were also performed. The

SUBMITTER: Chen YC 

PROVIDER: S-EPMC11774280 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature