Evaluation of radiomic feature harmonization techniques for benign and malignant pulmonary nodules.

ABSTRACT:

Background

Conventional methods for detecting lung cancer early are often qualitative and subject to interpretation. Radiomics provides quantitative characteristics of pulmonary nodules (PNs) in medical images, but variability in medical image acquisition is an obstacle to consistent clinical application of these quantitative features. Correcting radiomic features' dependency on acquisition parameters is problematic when combining data from benign and malignant PNs, as is necessary when the goal is to diagnose lung cancer, because acquisition effects may differ between them due to their biological differences.

Purpose

We evaluated whether we must account for biological differences between benign and malignant PNs when correcting the dependency of radiomic features on acquisi

SUBMITTER: Huchthausen C 

PROVIDER: S-EPMC11774441 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature