Sex differences in coronary atherosclerotic plaque activity using ¹⁸F-sodium fluoride positron emission tomography.

ABSTRACT:

Introduction

There are sex differences in the extent, severity, and outcomes of coronary artery disease. We aimed to assess the influence of sex on coronary atherosclerotic plaque activity measured using coronary ¹⁸F-sodium fluoride (¹⁸F-NaF) positron emission tomography (PET), and to determine whether ¹⁸F-NaF PET has prognostic value in both women and men.

Methods

In a post-hoc analysis of observational cohort studies of patients with coronary atherosclerosis who had undergone ¹⁸F-NaF PET CT angiography, we compared the coronary microcalcification activity (CMA) in women and men.

Results

Baseline ¹⁸F-NaF PET CT angiography was available in 999 participants (151 (15%) women) with 4282 patient-years of follow-up. C

SUBMITTER: Kwiecinski J 

PROVIDER: S-EPMC11774508 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature