Clinical Presentation and Course of Pulmonary Involvement in Chronic Nonbacterial Osteomyelitis.

ABSTRACT:

Objective

Pulmonary involvement in chronic nonbacterial osteomyelitis (CNO) is rare. Limited awareness results in diagnostic challenges, especially because malignancy or infection needs to be considered.

Methods

Based on a survey shared among centers participating in the Kerndokumentation Deutsches Rheumaforschungszentrum (Germany), this study investigated clinical and imaging presentations, demographic features, treatment response and outcomes of pulmonary involvement in CNO (pCNO). Magnetic resonance imaging and computed tomography images were read centrally by an experienced pediatric radiologist.

Results

Twenty-two patients with pCNO were included in this study. Among patients with CNO, pulmonary involvement was more common in girls (91% vs 62.8%, P = 0.006) and p

SUBMITTER: Hospach T 

PROVIDER: S-EPMC11774723 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature