Hydrophilic polymer coating delamination during neurointerventional treatment after microcatheter withdrawal: particulate identification through attenuated total reflection Fourier-transform infrared spectroscopy.

ABSTRACT: Hydrophilic coating embolism (HCE) is a rare and underreported complication in neurointerventional practice that can lead to serious medical consequences. Two endovascular procedures were interrupted at our institution after a cloudy liquid content was observed inside the rotating hemostatic valves (RHV) during microcatheter withdrawal. In both cases, the same type of microcatheter (Prowler Select Plus) and RHV (Merit) were being used, and coating dislodgement was suspected. Attenuated total reflection Fourier-transform infrared spectroscopy (ATR-FTIR) was used to identify the nature of such debris and compared it to samples obtained from different parts of an unused microcatheter and RHV. In an independent second analysis, an in vitro simulation of the withdrawal maneuver was condu

SUBMITTER: Muller SJ 

PROVIDER: S-EPMC11774725 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature