Prevalence and clinical impact of disseminated intravascular coagulation in acute aortic dissection: a nationwide cohort study.

ABSTRACT:

Background

Acute aortic dissection is a life-threatening cardiovascular emergency with high mortality rates. Disseminated intravascular coagulation (DIC) is a critical complication in patients with acute aortic dissection; however, its incidence and impact on outcomes remain inconclusive.

Objectives

This study aimed to evaluate DIC prevalence and prognosis in patients with aortic dissection.

Methods

We conducted a multicenter retrospective cohort study using data from the Japan Medical Data Center claims database between 2014 and 2022. DIC was diagnosed based on the criteria of the Japanese Association for Acute Medicine (JAAM-2) and the International Society on Thrombosis and Haemostasis (ISTH). We compared the in-hospital mortality between patients with and without

SUBMITTER: Murao S 

PROVIDER: S-EPMC11774824 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature