MRI-based intratumoral and peritumoral radiomics for assessing deep myometrial invasion in patients with early-stage endometrioid adenocarcinoma.

ABSTRACT:

Purpose

To evaluate the effectiveness of magnetic resonance imaging (MRI)-based intratumoral and peritumoral radiomics models for predicting deep myometrial invasion (DMI) of early-stage endometrioid adenocarcinoma (EAC).

Methods

The data of 459 EAC patients from three centers were retrospectively collected. Radiomics features were extracted separately from the intratumoral and peritumoral regions expanded by 0 mm, 5 mm, and 10 mm on unimodal and multimodal MRI. Then, various radiomics models were developed and validated, and the optimal model was confirmed. Integrated models were constructed by ensemble and stacking algorithms based on the above radiomics models. The models' performance was evaluated using the area under the curve (AUC).

Results

The multimodal MRI-ba

SUBMITTER: Yang J 

PROVIDER: S-EPMC11774896 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature