Protective effect of resveratrol on retinal damage in glaucoma: a systematic review and meta-analysis of preclinical studies.

ABSTRACT:

Introduction

Resveratrol, a polyphenolic compound commonly found in natural plants and fruits, exhibits potential in preventing optic nerve damage in glaucoma, as indicated by several animal studies. However, there is presently a dearth of relevant evidence available for comprehensive summarization.

Methods

In this study, we conducted an extensive search across 7 electronic databases, encompassing all pertinent animal studies for a systematic review and meta-analysis. Methodological quality was evaluated using SYRCLE's bias risk tool, with statistical analysis performed using Stata 17.0. The primary outcome measures included the survival of retinal ganglion cells and retinal thickness.

Results

The comprehensive analysis of the 30 included studies revealed that resvera

SUBMITTER: Zhang F 

PROVIDER: S-EPMC11774946 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature