Integrative multi-omics analysis reveals the translational landscape of the plant-parasitic nematode Meloidogyne incognita.

ABSTRACT: Root-knot nematodes (RKNs) of the genus Meloidogyne pose the most significant threats to global food security due to their destructive nature as plant-parasitic nematodes. Although significant attention has been devoted to investigating the gene transcription profiling of RKNs, our understanding of the translational landscape of RKNs remains limited. In this study, we elucidated the translational landscape of Meloidogyne incognita through the integration of translatome, transcriptome and quantitative proteome analyses. Our findings revealed numerous previously unannotated translation events and refined the genome annotation. By investigating the genome-wide translational dynamics of M. incognita during parasitism, we revealed that the genes of M. incognita undergo parasitic stage-specific

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC11775120 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature