An integrated approach to predict genetic risk for Mosquito-Borne diseases in the local Population of Tehsil Haripur, Khyber Pakhtunkhwa, Pakistan.

ABSTRACT: Highly variable response shown by individuals against mosquito-borne infections suggests that host genetic factors play an important role in determining mosquito-borne disease onset. Therefore, it is necessary to determine the genetic risk of these diseases in specific populations. The current study aimed to determine the percentage of individuals in the general population carrying mosquito-borne disease susceptibility and protection-related variants. This study initially aggregated mosquito-borne disease susceptibility and protection-related variants from all publically available data and literature. Afterward, the allele frequency was calculated 1009 genetic variants of 366 genes associated with susceptibility and protection to estimate the global prevalence in multiple ethnicities (Midd

SUBMITTER: Basri R 

PROVIDER: S-EPMC11775262 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature