Theta and beta power in the subthalamic nucleus responds to conflict across subregions and hemispheres.

ABSTRACT: The subthalamic nucleus is thought to play a crucial role in controlling impulsive actions. Networked among the basal ganglia and receiving input from several cortical areas, the subthalamic nucleus is well positioned to influence action selection when faced with competing and conflicting action outcomes. The purpose of this study was to test the dissociable roles of the dorsal and ventral aspects of the subthalamic nucleus during action conflict in patients with Parkinson's disease undergoing intraoperative neurophysiological recording and to explore a potential mechanism for this inhibitory control. We hypothesized that modulations of neurophysiological activity during action conflict would be more pronounced in the dorsal subthalamic nucleus compared with the ventral subthalamic nucleus

SUBMITTER: Bowersock JL 

PROVIDER: S-EPMC11775628 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature