Assessing and projecting the global impacts of Alzheimer's disease.

ABSTRACT:

Background

This study aims to assess the global burden of Alzheimer's disease (AD) from 1990 to 2030, with a focus on incidence, mortality, and disability-adjusted life years (DALY).

Methods

Data on the incidence rates, DALY rates, and death rates of AD across various geographic populations from 1990 to 2021 were obtained from the Global Burden of Disease (GBD) 2021 study. Generalized Additive Models (GAMs) were employed to forecast the disease burden from 2022 to 2030.

Results

The projected global burden of Alzheimer's disease from 2022 to 2030 indicates a decrease in DALYs, with an Estimated Annual Percentage Change (EAPC) of -1.44 (95% CI: -1.45, -1.42). Similarly, death rates and incidence rates also show a decline, with EAPCs of -1.80 (95% CI: -1.83, -1.77) and -

SUBMITTER: Zhang N 

PROVIDER: S-EPMC11775756 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature