Cardiac Response Dynamics in Newly Diagnosed Light-Chain Amyloidosis Patients With Early and High-Quality Hematologic Response.

ABSTRACT:

Background

The goal of hematological response has been well established in the treatment of systemic light chain amyloidosis. However, the pattern of cardiac response remains unknown.

Objectives

This study was designed to investigate the cardiac response dynamics in patients with an early and high-quality hematological response.

Methods

This retrospective study included newly diagnosed patients who achieved a hematological response of very good partial response or better within 3 months after treatment beginning. Four cardiac response criteria were tested at fixed time points (3, 6, 12, and 24 months after therapy initiation): cardiac complete response, cardiac very good partial response, cardiac partial response (carPR), and cardiac no response.

Results

A tota

SUBMITTER: Xu CY 

PROVIDER: S-EPMC11775800 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature