Resting-state brain functional connectivity in patients with chronic intractable pain who respond to spinal cord stimulation therapy.

ABSTRACT:

Background

Spinal cord stimulation (SCS) is widely accepted as a useful treatment for patients with intractable chronic pain. However, its effectiveness varies between individuals. Therefore, a tool for evaluating its effectiveness in advance is eagerly awaited. We examined whether resting-state functional magnetic resonance imaging as a diagnostic and prognostic tool can predict responsiveness to SCS.

Methods

Twenty-nine patients with intractable chronic pain participated in this study. Participants were divided into responder and non-responder groups based on a pain relief rate after SCS trials. All participants underwent resting-state functional magnetic resonance imaging scans before the SCS trials. We searched for functional connectivity that differed significantly in s

SUBMITTER: Ueno K 

PROVIDER: S-EPMC11775838 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature