Aperiodic component of the electroencephalogram power spectrum reflects the hypnotic level of anaesthesia.

ABSTRACT:

Background

Aperiodic (nonoscillatory) electroencephalogram (EEG) activity can be characterised by its power spectral density, which decays according to an inverse power law. Previous studies reported a shift in the spectral exponent α from consciousness to unconsciousness. We investigated the impact of aperiodic EEG activity on parameters used for anaesthesia monitoring to test the hypothesis that aperiodic EEG activity carries information about the hypnotic component of general anaesthesia.

Methods

We used simulated noise with varying inverse power law exponents α and the aperiodic component of EEGs recorded during wakefulness (n=62) and maintenance of general anaesthesia (n=125) in a diverse sample of surgical patients receiving sevoflurane, desflurane, or propofol, extrac

SUBMITTER: Widmann S 

PROVIDER: S-EPMC11775845 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature