Low albumin-to-creatinine ratios (ACR) are associated with poor outcomes in cancer patients.

ABSTRACT:

Background

The albumin-to-creatinine ratio (ACR) is known to predict prognosis in liposarcoma patients, but its role in other tumors remains unclear. This study aimed to evaluate the prognostic relationship between ACR and common solid tumors.

Methods

Data from the Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) between 2013 and 2022 were used to analyze patients under 65 years old with solid tumors. Patients were divided into a training cohort (n = 12,027) and a validation cohort (n = 7,985) using simple random sampling. Correlation analysis, Kaplan-Meier method, and restricted cubic spline analysis were conducted to explore ACR's relationship with overall survival (OS). Multivariable logistic regression assessed associations between ACR an

SUBMITTER: Zhao H 

PROVIDER: S-EPMC11776132 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature