The kidney reabsorption-related magnesium depletion score is associated with cardiovascular disease and longitudinal mortality in diabetic kidney disease patients.

ABSTRACT:

Background

The kidney reabsorption is essential for maintaining magnesium homeostasis. This study aims to explore the relationship between kidney reabsorption-related magnesium depletion score (MDS) and the occurrence of cardiovascular disease (CVD) and prognosis in diabetic disease kidney (DKD) patients.

Methods

We included 3199 DKD patients from the National Health and Nutrition Examination Survey (NHANES) database, including 1072 CVD patients. Weighted logistic regression analysis was used to explore the relationship between MDS and the occurrence of CVD. Weighted COX proportional hazards regression was used to explore the relationship between MDS and mortality. Stratified analysis was used to further validate. Finally, we assessed the predictive accuracy of MDS on surviv

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC11776169 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature