Coronary revascularisation deferral based on quantitative flow ratio or fractional flow reserve: a post hoc analysis of the FAVOR III Europe trial.

ABSTRACT:

Background

Safe deferral of revascularisation is a key aspect of physiology-guided percutaneous coronary intervention (PCI). While recent evidence gathered in the FAVOR III Europe trial showed that quantitative flow ratio (QFR) guidance did not meet non-inferiority to fractional flow reserve (FFR) guidance, it remains unknown if QFR might have a specific value in revascularisation deferral.

Aims

We aimed to evaluate the safety of coronary revascularisation deferral based on QFR as compared with FFR.

Methods

Patients randomised in the FAVOR III trial in whom PCI was deferred in at least one coronary artery, based on QFR or FFR>0.80, were included in the present substudy. The primary outcome was the 1-year rate of major adverse cardiac events (MACE), with results report

SUBMITTER: Andersen BK 

PROVIDER: S-EPMC11776405 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature