Inductively Coupled Plasma Mass Spectrometry Performance for the Measurement of Key Serum Minerals: A Comparative Study With Standard Quantification Methods.

ABSTRACT:

Background

Inductively coupled plasma mass spectrometry (ICP-MS) is widely used for the accurate measurement of minerals. However, its application to serum essential mineral measurement has not been fully evaluated. The present study aimed to assess the performance of ICP-MS for serum minerals by comparing its measurements to those obtained using standard quantification methods.

Methods

Cross-sectional data were collected from 282 participants from a single facility in Japan. Serum concentrations of eight key minerals, namely sodium, potassium, calcium, phosphorus, magnesium, iron, zinc, and copper, measured via ICP-MS and standard methods were compared using Passing-Bablok regression and Bland-Altman plots.

Results

All minerals, except phosphorus, exhibited good agre

SUBMITTER: Kojo K 

PROVIDER: S-EPMC11776499 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature