Cerebellar contribution to emotion regulation and its association with medial frontal GABA level.

ABSTRACT: As a tactic to regulate emotions, distancing involves changing perspectives to alter the psychological distance from stimuli that elicit emotional reactions. Using magnetic resonance spectroscopy and functional magnetic resonance imaging, this study aimed to examine (i) whether the neural correlates of emotion upregulation via distancing differ across emotional valence (i.e. emotional responses toward positive and negative pictures), and (ii) whether the gamma-aminobutyric acid (GABA) concentration in the medial prefrontal cortex (MPFC), one of the crucial areas of emotion regulation, is correlated with brain activity related to either negative or positive emotion upregulation. Thirty-four healthy Japanese adults participated in this study. Compared to the condition involving positive emot

SUBMITTER: Oboshi Y 

PROVIDER: S-EPMC11776713 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature