Prognostic value of pre-ablation stimulated thyroglobulin in children and adolescents with differentiated thyroid cancer.

ABSTRACT:

Aim

To investigate the prognostic value of pre-ablation stimulated thyroglobulin (ps-Tg) in children and adolescents with persistent differentiated thyroid cancer (DTC) following initial radioiodine therapy (RAI).

Materials & methods

Patients were classified into "no clinical evidence of disease" (NED), "biochemical persistent disease" (BPD), and "structural/functional persistent disease" (S/FPD) groups, based on their therapeutic response to initial RAI. BPD patients were further categorized as incomplete response (IR) or Non-IR; S/FPD patients were categorized as remission or Non-remission. Receiver operating characteristic (ROC) curves were used to assess the predictive value of ps-Tg for long-term prognosis. Univariate and multivariate regression analyses were performed

SUBMITTER: Wang C 

PROVIDER: S-EPMC11776856 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature