Frozen versus fresh embryo transfer in women with low prognosis for in vitro fertilisation treatment: pragmatic, multicentre, randomised controlled trial.

ABSTRACT:

Objective

To test the hypothesis that a freeze-all strategy would increase the chance of live birth compared with fresh embryo transfer in women with low prognosis for in vitro fertilisation (IVF) treatment.

Design

Pragmatic, multicentre, randomised controlled trial.

Setting

Nine academic fertility centres in China.

Participants

838 women with a low prognosis for IVF treatment defined by ≤9 oocytes retrieved or poor ovarian reserve (antral follicle count <5 or serum anti-Müllerian hormone level <8.6 pmol/L).

Interventions

Eligible participants were randomised (1:1) to undergo either frozen embryo transfer or fresh embryo transfer on the day of oocyte retrieval. Participants in the frozen embryo transfer group had all of their embryos cryopreserved and un

SUBMITTER: Wei D 

PROVIDER: S-EPMC11778674 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature