Comparative effectiveness of initial computed tomography and invasive coronary angiography in women and men with stable chest pain and suspected coronary artery disease: multicentre randomised trial.

ABSTRACT:

Objective

To assess the comparative effectiveness of computed tomography and invasive coronary angiography in women and men with stable chest pain suspected to be caused by coronary artery disease.

Design

Prospective, multicentre, randomised pragmatic trial.

Setting

Hospitals at 26 sites in 16 European countries.

Participants

2002 (56.2%) women and 1559 (43.8%) men (total of 3561 patients) with suspected coronary artery disease referred for invasive coronary angiography on the basis of stable chest pain and a pre-test probability of obstructive coronary artery disease of 10-60%.

Intervention

Both women and men were randomised 1:1 (with stratification by gender and centre) to a strategy of either computed tomography or invasive coronary angiography as the

SUBMITTER: DISCHARGE Trial Group 

PROVIDER: S-EPMC11778908 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature