Re-emergence of Oropouche virus between 2023 and 2024 in Brazil: an observational epidemiological study.

ABSTRACT:

Background

Oropouche virus is an arthropod-borne virus that has caused outbreaks of Oropouche fever in central and South America since the 1950s. This study investigates virological factors contributing to the re-emergence of Oropouche fever in Brazil between 2023 and 2024.

Methods

In this observational epidemiological study, we combined multiple data sources for Oropouche virus infections in Brazil and conducted in-vitro and in-vivo characterisation. We collected serum samples obtained in Manaus City, Amazonas state, Brazil, from patients with acute febrile illnesses aged 18 years or older who tested negative for malaria and samples from people with previous Oropouche virus infection from Coari municipality, Amazonas state, Brazil. Basic clinical and demographic data were c

SUBMITTER: Scachetti GC 

PROVIDER: S-EPMC11779697 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature