The value of MRI in differentiating ovarian clear cell carcinoma from other adnexal masses with O-RADS MRI scores of 4-5.

ABSTRACT:

Objective

To assess the utility of clinical and MRI features in distinguishing ovarian clear cell carcinoma (CCC) from adnexal masses with ovarian-adnexal reporting and data system (O-RADS) MRI scores of 4-5.

Methods

This retrospective study included 850 patients with indeterminate adnexal masses on ultrasound. Two radiologists evaluated all preoperative MRIs using the O-RADS MRI risk stratification system. Patients with O-RADS MRI scores of 4-5 were divided into a training set (n = 135, hospital A) and a test set (n = 86, hospital B). Clinical and MRI features were compared between CCC and non-CCC patients. Analysis of variance and support vector machine were used to develop four CCC prediction models. Tenfold cross-validation was applied to determine the hyperparameters. M

SUBMITTER: Lin L 

PROVIDER: S-EPMC11780052 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature