Severe cutaneous drug toxicity following disitamab vedotin treatment for metastatic gastric cancer: a case report.

ABSTRACT:

Background

This study reports a case of severe cutaneous toxicity in a patient with metastatic gastric cancer induced by disitamab vedotin, emphasizing the need for careful monitoring and management in such treatments.

Case presentation

A 71-year-old female was admitted to hospital complaining of serious rashes following the first cycle of disitamab vedotin regimen for metastatic gastric cancer. The doctor diagnosedtoxic epidermal necrolysis (TEN) induced by the drug. The patient received high-dose methylprednisolone due to the side effects. This resulted in a gradual improvement of symptoms.

Conclusion

During the use of disitamab vedotin, patients need to be monitored for severe skin toxicity.

SUBMITTER: Luping Z 

PROVIDER: S-EPMC11780377 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature