Flexible Nanostructured NiS-Based Electrochemical Biosensor for Simultaneous Detection of DNA Nucleobases.

ABSTRACT: Herein, we demonstrate a one-step, scalable, solution-processed method for the growth of nickel sulfide (NiS) nanostructures using single-source precursors (SSPs) on a flexible substrate as a versatile framework for simultaneous detection of four DNA nucleobases. The as-grown NiS nanostructures exhibit a broad bandgap range and spherical morphology with high surface area and significant porosity, as confirmed by SEM, TEM, and BET surface area analysis. Consequently, the NiS/Ni-foam electrode exhibited remarkable electrochemical performance toward the oxidation of A, G, T, and C due to its large surface area, high electrode activity, and efficient electron transfer capacity. Under the optimum conditions, the electrode demonstrated selective and simultaneous detection of all four nucleobases

SUBMITTER: Gaikwad PN 

PROVIDER: S-EPMC11780467 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature