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A systematic review of the association between biological markers and environmental stress risk factors for adolescent depression.


ABSTRACT:

Introduction

Although the aetiology and pathophysiology of depression are multifactorial, to date most studies have examined either biological or environmental mechanisms without looking at the integration of both; with most studies conducted in high-income countries (HICs). Therefore, we conducted a systematic review of worldwide studies investigating the relationship between biological and environmental stress risk factors for major depressive disorder (MDD) in adolescence.

Methods

We searched MEDLINE (via Ovid), PsycINFO, Cochrane Database of Systematic Reviews, Web of Science (Core Collection), Lilacs, African Journals Online and Global Health for prospective and cross-sectional studies that examined the association between biological markers and environmental stress ris

SUBMITTER: Zajkowska Z 

PROVIDER: S-EPMC11780543 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature