Effect of invasive tests during pregnancy on perinatal transmission of hepatitis B infection: a scoping review.

ABSTRACT: Prenatal and intrapartum invasive tests are possible mechanisms of mother to child transmission (MTCT) of hepatitis B virus (HBV). The viral activity can affect the MTCT risk after invasive tests, but the evidence is scarce. This scoping review discussed the effects of prenatal or intrapartum invasive tests on the risk of HBV MTCT. The risk of MTCT after amniocentesis was low among hepatitis B infected pregnant individuals with negative hepatitis B e antigen (HBeAg) statuses or HBV DNA < 7 log₁₀ IU/mL, and comparable to those that did not undergo prenatal invasive tests. Amniocentesis could increase the risk of MTCT among women with seropositive HBeAg statuses or HBV DNA ≥ 7 log₁₀ IU/mL, but there were no MTCT among these women who received antiviral treatment. Data o

SUBMITTER: Cheung KW 

PROVIDER: S-EPMC11780714 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature